Fast and directly correlated integration of light and electron microscopy
We developed a targeted approach that allows to image specific tissue features, like organelles, cell processes, and nuclei at different...
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News and Events from Flanders BioImaging
Jul 12, 20231 min read
Checking the mobility of a promising vision impairment therapeutic
Globally, over 2 billion people suffer from vision impairment. Deglycating enzyme fructosamine-3-kinase (FN3K) was recently proposed as a...
Jul 12, 20231 min read
Oral peptide delivery with nanocapsules
The delivery of therapeutic peptides via the oral route remains one of the biggest challenges in the pharmaceutical industry. Recently,...
Jul 12, 20231 min read
Tracking PEGylated rhDNase in lung tissue
In this paper, we investigated the mechanisms promoting the extended lung retention of PEG-rhDNase conjugates using cell culture models...
Jul 12, 20231 min read
A non-invasive marker for spinal cord injury damage
[11C]-UCB-J PET/CT imaging is a non-invasive marker for SV2A loss following spinal cord injury. SV2A PET may provide an objective measure...
Jul 12, 20231 min read
Imaging mutant huntingtin in the brain
[11C]CHDI-39 180R allowed for non-invasive monitoring of mHTT pathology in the brain and could track region and time-dependent...
Jul 12, 20231 min read
Promising biomarkers for Alzheimer's disease
Resting-state co-activation patterns are a promising candidate in the development of a diagnostic, and potentially, prognostic RS-fMRI...
Jul 12, 20231 min read
Biomarkers for Huntington's disease
Altered cortico-striatal FC in SuCN - LCN regions in the 12-month-old zQ175DN mice Reduced FC in DMLN and ACN regions at 6- and...
Jul 12, 20231 min read
Modelling the therapeutic potential of tonabersat
In this preclinical study, we evaluated the possible therapeutic potential of tonabersat for the treatment of glioblastoma. Tonabersat is...
Jul 12, 20231 min read
The state of the art of preclinical precision irradiation
With the advent of preclinical radiation research platforms, many radiotherapy research centers are now able to investigate the radiation...
Jul 12, 20231 min read
The feasibility of PET/MRI guided radiotheraphy
In this study we showed the feasibility of PET/MRI guided sub-volume boosting in an animal model for glioblastoma using a preclinical...
Jul 12, 20231 min read
Bridging the gap with our small-animal radiation research platform
In this paper we tried to mimic the standard-of-care for the treatment of glioblastoma in patients using an animal model. For radiation...
Jul 12, 20231 min read
Label-free second harmonic imaging of microtubules
Unraveling the molecular determinants behind label-free second harmonic imaging of microtubules. As published in: Van Steenbergen, V.,...
Jul 12, 20231 min read
Structural imaging of full thickness of colon ridges
Physiologically relevant imaging of the ENS and epithelium in the proximal colon of Wnt1Cre/WT Rosa26GCaMP3/WT mice. Structural imaging...
Jul 12, 20231 min read
Non-descanned second harmonic imaging
Recordings of simultaneous, non-descanned forward second harmonic generation (SHG) and non-descanned backward 2PE autofluorescence in...
Jul 12, 20231 min read
Timelapse imaging of macrophage-ENS interactions
We performed live timelapse imaging of Macrophage – ENS interactions in Wnt1Cre/WT Rosa26tdT/WT Cx3cr1GFP/WT double reporter mice using...
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